Many autistic users experience heightened reactions to bright or saturated colors, which can cause visual stress and cognitive overload. Natural color schemes drawn from muted earth tones or pastel variations provide visual clarity while minimizing sensory overload. These colors include soft blues, gentle greens, and warm beiges. When using these colors, maintain sufficient contrast for text legibility between 3:1 for large text and 4.5:1 for small text to help create a more comfortable viewing experience without creating harsh visual differences that might cause discomfort.

Also, consider implementing color themes that users can customize according to their preferences. This approach acknowledges the spectrum nature of autism and allows users to adjust the interface to their specific sensory needs.